Handlung
Zwei Jahre sind inzwischen vergangen, als Peter Parker von einer genmutierten Spinne gebissen wurde und sein Leben sich radikal verändert hat. Bei der Verbrechensbekämpferei lässt er sein College-Studium schleifen und verspätet sich permanent bei seinen beiden Jobs. Zu allem Überfluss muss Peter mit ansehen, wie Mary Jane im Gegensatz zu ihm ihr Leben meistert. Nun allerdings streckt ein neuer Bösewicht namens Dr. Octavius seine metallischen Tentakel nach der Zivilisation aus. Mit ihm ist nicht zu spaßen..
Regie
Besetzung
Tobey Maguire
Spider-Man / Peter Parker
Kirsten Dunst
Mary Jane Watson
James Franco
Harry Osborn
Alfred Molina
Doc Ock / Otto Octavius
Rosemary Harris
May Parker
J.K. Simmons
J. Jonah Jameson
Donna Murphy
Rosalie Octavius
Daniel Gillies
John Jameson
Dylan Baker
Dr. Curt Connors
Bill Nunn
Joseph 'Robbie' Robertson
Vanessa Ferlito
Louise
Aasif Mandvi
Mr. Aziz
Willem Dafoe
Green Goblin / Norman Osborn
Cliff Robertson
Ben Parker
Ted Raimi
Hoffman
Elizabeth Banks
Miss Brant
Bruce Campbell
Snooty Usher
Gregg Edelman
Dr. Davis
Elya Baskin
Mr. Ditkovitch
Mageina Tovah
Ursula
Daniel Dae Kim
Raymond
Hal Sparks
Elevator Passenger
Joel McHale
Mr. Jacks
Stan Lee
Man Dodging Debris
Kelly Connell
Dr. Isaacs
Brent Briscoe
Garbage Man
Emily Deschanel
Receptionist
Jason Fiore-Ortiz
Henry Jackson
Scott Spiegel
Man on Balcony
Andy Bale
OsCorp Executive
Christine Estabrook
Mrs. Jameson
Molly Cheek
Society Woman
John Paxton
Houseman
Joy Bryant
Woman at Web
Joanne Baron
Skeptical Scientist
Peter McRobbie
OsCorp Representative
Timothy Jerome
Injured Scientist
Taylor Gilbert
Mrs. Watson
Peter Vouras
Stage Manager
Donnell Rawlings
Pizza "Heist" Witness
Zachry Rogers
Boy saved by Spider-Man
Ella Rogers
Girl saved by Spider-Man
Louis Lombardi
Poker Player
Marc John Jefferies
Amazed Kid
Roshon Fegan
Amazed Kid
Brendan Patrick Connor
Theater Traffic Cop
Reed Diamond
'Algernon'
Dan Callahan
'Jack'
Elyse Dinh
Violinist
John Landis
Doctor
Tim Storms
Chainsaw Doctor
Susie Park
Clawing Nurse
Patricia M. Peters
Screaming Nurse
Michael Edward Thomas
Man at Fire
Anne Betancourt
Woman at Fire
Venus Lam
Child in Burning Building
Bill E. Rogers
Fireman
Joe Virzi
Fireman
Tom Carey
Train Conductor
Jopaul Van Epp
Boy with Mask
Weston Epp
Boy with Mask
Peter Allas
Train Passenger
Brianna Brown
Train Passenger
Bill Calvert
Train Passenger
Tony Campisi
Train Passenger
Joey Diaz
Train Passenger
Chloe Dykstra
Train Passenger
Simone Gordon
Train Passenger
Dan Hicks
Train Passenger
Julia Max
Train Passenger
Savannah Pope
Train Passenger
Timothy Patrick Quill
Train Passenger
Jill Sayre
Train Passenger
Rickey G. Williams
Train Passenger
Michael Arthur
NYPD Officer (uncredited)
Frank Bonsangue
Pizza Man (uncredited)
Cindy Cheung
Chinese Daughter (uncredited)
Phil LaMarr
Train Passenger (uncredited)
Andre M. Johnson
Fireman 2 (uncredited)
Peter Cincotti
Piano Player in Planetarium (uncredited)
Troy Metcalf
Blue Collar Guy (uncredited)
Scott Ross
Pedestrian (uncredited)
Bonnie Somerville
Screaming Woman (uncredited)
Wesley Volcy
Columbia University Student (uncredited)
Lou Volpe
Man at Web (uncredited)
Garrett Warren
Bearded Doctor (uncredited)
Joseph M. Caracciolo
Priest at Mary Jane's Wedding (uncredited)
David Boston
Pedestrian (uncredited)
Sho Brown
Passenger (uncredited)
Sal Ardisi
Parent (uncredited)
Edward Johnson
Planetarium (uncredited)
Grant Curtis
Hot Dog Vendor (uncredited)
Vince Cupone
Victim (uncredited)
William E. Corcoran
Stock Broker (uncredited)
Mohammed Hassan
Middle Eastern Taxi Driver (uncredited)
Rachel Lehrer
Hot Girl (uncredited)
Gene LeBell
Train Passenger (uncredited)
Lorelei Llee
Bank Employee (uncredited)
Joseph Nelson
Extra (uncredited)
Claudia Katz Minnick
Robbie's Assistant (uncredited)
Ronn Ozuk
Cop (uncredited)
Denney Pierce
Train Passenger (uncredited)
Carla Rhodes
Phone Booth Girl (uncredited)
Randy Reinholz
Train Passenger (uncredited)
Rachelle Roderick
Jane, Engineer (uncredited)
Angel Katherine Taormina
Female Onlooker on Street (uncredited)
Douglas Swander
Train Passenger (uncredited)
Jimmy Star
Reporter (uncredited)
Jack Wetherall
Train Passenger (uncredited)
Ken Wharton
Uptight Businessman (uncredited)
Henry Truong
Doc Ock Lab Assistant #2 (uncredited)
Al Collado
Cab Driver (uncredited)
Lee Cogburn
Train Passenger (uncredited)
Sam Raimi
University Student with Bag (uncredited)
John Cameron
Man Buying 'Spider-Man No More' Newspaper (uncredited)
Spider-Man Filmreihe
