Pepper Ann

Pamela Adlon

Moose (voice)

Kathleen Wilhoite

Pepper Ann (voice)

Danny Cooksey

Milo (voice)

Clea Lewis

Nicky (voice)

April Winchell

Mom (voice)

Jeff Bennett

Craig Bean / Dieter Liederhosen / Bob / Additional Voices (voices)

Kath Soucie

Cissy Rooney / Additional Voices (voice)

Candi Milo

Constance Goldman (voice)

Jenna Von Oÿ

Trinket St. Blair (voice)

Tino Insana

Uncle Jojo (voice)

Susan Tolsky

Aunt Janie (voice)

Cree Summer

Tessa and Vanessa James / Additional Voices (voice)

Alex Trebek

Paddi Edwards

Vera Groober-Schwartz (voice)

Don Lake

Mr. Sherman Finky (voice)

Don Adams

Principal Hickey (voice)

Jess Harnell

Male Scientist / Nigel / Mailman (voice)

Mark Hamill

Kathy Najimy

Coach Doogan (voice)

Tara Strong

Brenda (voice)

Jim Cummings

Mr. Roland Carter (voice)

Kenn Michael

Malik / Lamar Abu Dabe (voice)

Maurice LaMarche

Chuck Pearson / Jeweler (voice)

Jodi Benson

Isabel Sanford

Bernice (voice)

Hedy Burress

Effie Shrugg (voice)

Bebe Neuwirth

Ms. Bladdar (voice)

Hadley Kay

Lauren Tom

Nicole Sullivan

Tundra Woman (voice)

Evel Knievel

Jason Marsden

Prep School Guy (voice)

Wallace Langham

Wayne Macabre (voice; uncredited)

Shaun Fleming

Cookie (voice)

Max Brooks

Worried Executive #1 (voice)

Phil LaMarr

Stubborn Executive / Hippie Guy (voice)

Cam Clarke

Stewart Walldinger (voice)

Sue Rose

Moira (voice)

Luke Perry

Stewart Walldinger (voice)

Kimmy Robertson

Gwen Mezzrow (voice)

Max Casella

Additional Voices (voice)

Julia Sweeney

Ms. Sneed (voice)

Karen Duffy

Sketch (voice)

Meredith Scott Lynn

Poison (voice)

Brittany Murphy

Tank (voice)

Julia Duffy

Aunt Fanny (voice)

Ryan O'Donohue

Damian (voice)

Francesca Marie Smith

Damiana (voice)