Room 104

Jennifer Lafleur

Karen

Kristina Harrison

Mother

Jon Bass

Hamster

Jenny Leonhardt

Larry

Sameerah Luqmaan-Harris

Deborah

Melonie Díaz

Meg

Clark Duke

Jarod

Orlando Jones

Samuel

James Van Der Beek

Scott

Tony Todd

The Father

Davie-Blue

Jennifer

Ethan Kent

Ralph

Gavin Kent

Ralphie

Ross Partridge

Bradley

Onur Tukel

Erol

Abby Ryder Fortson

Elle

Josephine Decker

Rosie

Luke Wilson

Remus

Christine Woods

Roma

Logan Miller

Logan

Mark Duplass

Graham Husker

Jillian Bell

Sam

Dave Bautista

Raw Dog Avalanche

Melissa Fumero

Eva

Kevin Nealon

Harry

Shannon Purser

Megan

Kendra Carelli

Casey

Gary Cole

Chip Crawford

Linda Lavin

Enid

Harvey Guillén

Luke

Cobie Smulders

Scientist

Benjamin Papac

Olivia Crocicchia

Alison Jaye Horowitz

Leonardo Lam

Bruce

Lily Gladstone

Abby

Mary Mouser

Adrienne

Meilee Condron

Sonia (Girl)

Macon Blair

George

Carl De Gregorio

Dad

Jay Duplass

Daniel

Will Tranfo

Patrick

Frank Ashmore

Older Patrick

Karan Soni

Anish

Poorna Jagannathan

Divya (voice)

Darin De Paul

Man On Tape (voice)

Dendrie Taylor

Housekeeper

Sarah Hay

Girl

Matthew Bellows

Man (voice)

Adam Foster

Noah

Nat Wolff

Joseph

Amy Landecker

Joan

Mae Whitman

Liza

Spencer Garrett

Dr. Dan Benich

Konstantin Lavysh

Boris

Veronica Falcón

Rosa

Biff Wiff

Edgar

Keir Gilchrist

Alex

Hugo Armstrong

Steve

Brian Hostenske

Josh

Michael Chandler

Reporter (voice)

Marieve Herington

Reporter (voice)

Jason Hightower

Reporter (voice)

Cheryl Texiera

Reporter (voice)

Natalie Morgan

Greta

Keta Meggett

Rayna

Mark Kelly

Contractor

Stephen Rannazzisi

JR (voice)

Channon Dade

Front Desk Receptionist

Jesse Springer

Fight Commentator

Faruq Tauheed

Man In Next Room

Philip Baker Hall

Charlie

Ellen Geer

Lorraine

Lo Mutuc

Gracie

Tom Lenk

Matty

Rainn Wilson

Jim

Frank Ellis

Mr. Mulvahill

Michael Shannon

Nathan

Judy Greer

Darla Andrews

Katya Zamolodchikova

Ochin'priyatna

Tom Clark

Burly Cop

Fred Maske

Scrawny Cop

Kent Osborne

Dan

Mark Proksch

Gene

Michole Briana White

Officer Pankin

Leonora Pitts

Dolly Wells

Catherine

Brian Tyree Henry

Arnold

Ginger Gonzaga

Vicki

Phil Matarese

P-Dawg

Chris McLaughlin

Chris

Jeffrey G. Barnett

Masked Man

Marlene Forte

Mom

Natalie Morales

Jess

Stephanie Allynne

Sarah

Katie Aselton

Helen

Julian Grant

Roger

Sheaun McKinney

Charles

Mahershala Ali

Franco

James Earl

Ollie

Joel Allen

Donovan

Nicholette Dixon

Upperclass Woman #1

Jaclyn Jasgur

Drunk Freshman

Anita Kalathara

Emily

Zane Pais

Jon

Mary Wiseman

Josie

Trevor Wooldridge

Frat boy

Eric Edelstein

Swofford

Dale Dickey

Sharon

Robert Longstreet

Allan

Tom Woodruff Jr.

Elmer

Arturo Castro

Craig

François Chau

Dr. Blake

Gina Gallego

Denise

Iyana Halley

Zohara

Catalina Sandino Moreno

Maria

James Babson

Willis

Sam Richardson

Greg

Steve Little

Randy

Fred Melamed

Narrator (voice)

Julianna Barwick

Nina

Atsuko Okatsuka

Woman

Tony Plana

Bracamonte

Angie Cepeda

Dolores

Timm Sharp

Brandon

Julian Acosta

Older Brother

Rhoda Pell

Ghost Mother

Josh Fadem

Ted

Marielle Scott

Nina

David Paymer

Robert

Jeremy Guskin

Young Robert

Ashley Marie Jones

Camille

Jessica Makinson

Mario Revolori

Lou

Lily Mae Harrington

Beth

Susanna Harter

Veronica

Aislinn Paul

Young Jean

June Squibb

Jean

Paul F. Tompkins

Louis

Aasif Mandvi

Mediator

Ian Merrigan

Joe (voice)

David Boat

(Voice)

Hari Nef

Katherine

Bernard David Jones

Justin

Griffin Morgan

Kid

Josie M. Parker

Young Sam

Natalie Woolams-Torres

Tamara

Vivian Bang

Jaimie

Finn Roberts

Walker

Dana Adam Shapiro

Derek

Breeda Wool

Poppy March

Jason David

Will

Ron Funches

Skylar Gray

Maddie

Erinn Hayes

Sadie Stanley

Ashley Kaul / Jules

Kristina Hanna

Finnegan George

Pia Shah

Tanya